TOP 15 Best Vasodilator Supplements Reviewed 2021

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Best Vasodilator Supplements & TOP 15 Supplement Reviews 2021

Looking for the best Vasodilator supps?

Whether you are trying to increase muscle pumps, get bigger veins, get better performance in the bedroom or even lower blood pressure, this list of 15 of the best vasodilator supplements has something for you.

First I want to briefly explain the most common and effective vasodilator supplements so you know what to look out for and what will help you the most.

Then we can dive into the 15 reviews of the best vasodilator supplements.

man holding dumbbell - fitness concept

What Are Vasodilator Supplements? What Do They Do?

Vasodilation is the opening or widening of blood vessels. The molecule responsible for this in the body is Nitric Oxide or NO for short.

Vasodilator supplements increase NO directly or indirectly by being a precursor to NO, causing the body to create more NO, or preventing the body from breaking down existing NO.

What does this mean for muscle building and gym performance?

Vasodilation causes the muscle to look bigger and makes veins stand out.

As cool as this looks, vasodilation supplements also have a purpose beyond just appearances.

Vasodilation promotes blood flow and triggers muscle growth.

Do they have side effects?

Since vasodilation widens the blood vessels, they lower blood pressure. Too much vasodilation may lead to a dizzy feeling.

Generally, when taken according to package instructions, vasodilation supplements are safe and cause no side effects, however, if you take too much you may get stomach pain, diarrhea, dizziness or headache.

What ingredients you should know about and keep in mind before buying vasodilator supplements.

Best Vasodilator Supplement Lineup

protein powder in scoop with vitamins


The ideal dose for L-arginine if you are using it as a pre-workout supplement is 3 to 6 grams. L-Arginine is used to produce Nitric Oxide in the body via the enzyme Nitric Oxide Synthase.

Good to know: L-citrulline is a precursor to L-Arginine, but L-Citrulline is actually preferred over L-Arginine because oddly enough, it raises L-arginine levels in the blood more than L-arginine itself.

Arginine Alpha-Ketoglutarate

A manufactured form of L-arginine said to be more effective and longer lasting than L-arginine, but there are no studies or science to back this up. It does, however, increase levels of plasma L-arginine.


Nitrosigine is a manufactured chemical composed of L-arginine boded to silicone. It raises NO significantly and consequently makes a great vasodilation supplement.


A good dose of L-Citrulline is around 3 grams. L-Citrulline is a precursor to L-arginine and is actually superior at raising blood levels of L-Arginine.

L-arginine is used to make the vasodilating molecule Nitric Oxide.


The Ideal Dose of Glutathione is 200 mg taken with just 2 grams of L-Citrulline. Glutathione when paired with L-Citrulline increases NO levels more than L-Citrulline alone.

Citrulline Malate

Citrulline malate is a less potent form of L-Citrulline. 1 gram of L-citrulline is about equal to 1.8 g of Citrulline Malate because Citrulline malate is 2 parts Citrulline and one part Malate.

Vitamin B3 – Niacin- Nicotinic Acid

Vitamin B3, also known as Niacin, is a vasodilator. It can temporarily reduce blood pressure as a result of vasodilation.

Niacin is sufficient doses may also cause your face to flush and feel hot for a short time. This side effect is harmless but some find it uncomfortable.


Taurine is a vasodilator that activates Gaba receptors and causes a relaxing of blood vessels and lowers blood pressure.

Beets – a natural NO Booster

The Ideal Dose of beet root, if you are using it as a vasodilator, depends on the level of nitrates in the beets.

If its pure beet root you need about an lb. of raw beets. It is best to use this vasodilating supplement with a NO potentiator like Glutathione or extender like L-Norvaline to get good results.


L-Norvaline increases vasodilation by inhibiting the molecule that breaks down L-arginine. L-Arginine is necessary to create N.O. L-Norvaline extends or lengthens the effect of nitric oxide and can increase production of NO significantly.


Betaine increase blood levels of nitrate, which can increase NO, and vasodilation.


L-Theanine is an amino acid found in tea. It is known to have relaxing properties and is often paired with Caffeine to take the jittery edge of caffeine.

L-Theanine reduces blood pressure and counters the vasoconstricting effect of caffeine.


Beta alanine raises blood levels of Carnosine. Carnosine is necessary to make Nitric Oxide synthase, which is a molecule needed to create NO.

Be aware, supplementation od Beta Alanine may give you tingles or a pins and needles type feeling that some people like but others find annoying.

If your pre-workout is making you feel tingly, it might be because of a high dose of Beta-alanine.

Pine Bark Extract

Studies show that Pine Bark Extract stimulates Nitric Oxide and causes vasodilation.


Quercetin, a natural plant flavonol found in apples and other fruits and veggies, reduces blood pressure and has a vasodilator effect when used as a supplement.

Grape Seed Extract

Polyphenols from grape seed extract are strong vasodilating supplements.

ALA or Alpha Linolic Acid

Shown to be a vasodilator, possible because it also helps raise levels of glutathione.

Fit young woman drinking pre workout drink in the gym

Now that you know what ingredients really deliver the goods, let’s see which products out there contain these proven vasodilation ingredients in meaningful doses.

Top 15 Best Vasodilator Supplements Reviewed 2021

N.O. XT Nitric Oxide Supplement

Review: Studies show the combination of L-Citrulline with glutathione intensifies increases in nitrite and NOx levels.

This N.O. XT contains just 1.5 grams if L-Citrulline, but it also has 200 mg of glutathione that helps the level of NO remain high, making this formula an effective vasodilator.


  • 30 servings at well under 1 dollar per serving.
  • Combined dose of L-Citrulline and Gluthionine for synergistic NO boost.
  • 500 mg of blood vessel dilating Nitrosigine Arginine.


  • Larger guys may need a larger dose to feel the effects.


Straightforward and simple formula, one of the best supplement for vasodilation.

L-Citrulline DL-Malate 2:1 Powder

Review: Pure L-Citrulline DL-Malate 2:1 Powder in a ratio of two parts Citrulline and one part malate. This is easily the most budget-friendly vasodilator supplement and it is effective too.

While Citrulline is a precursor to NO boosting Arginine, it actually is absorbed better and increases arginine more in the blood than supplementing arginine itself.

Easily one of the most recommended vasodilator supplements for bodybuilding.


  • 100% Pure L-Citrulline DL-Malate 2:1 Powder.
  • 83 servings in one bag.
  • Very inexpensive.


  • It is a powder so you need to put it in a capsule. Has a sour taste if you decide to mix it in a drink.


One of the best vasodilator supplements for 2021 for your money.

Sheer Strength Sheer Nitro Pre-Workout

Review: This is a solid, simple, stim free vasodilation supplement with high enough doses of the effective ingredients to place it at number three on this list.

It has 6 grams of NO boosting Citrulline Malate paired with other vasodilators like Betaine and Taurine.

The formula also includes 750 mg of Nitrosigine, which is arginine bonded to silicon, which has been shown to increase NO levels and vasodilation.


  • 6 Grams of proven vasodilator Citrulline Malate.
  • 5 grams of Taurine a known vasodilator.
  • Contains Nitrosigine, proven vasodilator.


  • Gritty texture.


The stim free pre-workout for pumps without tingles or itching.

Legion Pulse Pre-Workout

Review: This popular and highly regarded pre-workout supplement will give you great muscle pumps and a shot of energy at the same time.

The 8 generous grams of L-Citrulline DL-Malate 2:1 and a large 350 mg dose of caffeine, are guaranteed to contribute to your success at the gym.

The formula also includes Carnosyn brand Beta-alanine, which may cause tingles, but also increases nitric oxide because it is a precursor to nitric oxide synthase.


  • 8 grams of L-Citrulline DL-Malate 2:1.
  • Contains Vasodilators Betaine and Taurine.
  • Includes L-Theanine which takes the jittery edge off of caffeine, and also acts as a vasodilator.


  • Expensive Price per serving.


Energy and Pumps, a good vasodilator supplement.

GEC N.O. - Flo Nitric Oxide

Review: This vasodilating supplement is on point with proven ingredients like L-Citrulline DL-Malate and Nitrosigine.

In addition to these two awesome ingredients, this formula is one of the only supplements I found that also has both L-glutathione and L-Norvaline. L-glutathione is special because it synergistically boosts the activity of L-Citrulline DL-Malate 2:1 giving you a bigger bang for your buck.

L-Norvaline is also somewhat rare ingredient that extends the life of nitric oxide so your pumps last longer.


  • Includes nitric oxide extender L-Norvaline.
  • Includes L-Citrulline enhancing glutathione.
  • 6 grams of L-Citrulline DL-Malate 2:1.


  • Pricy, but worth it.


Amplifies and extends pumps beyond the ingredients found in other vasodilator supplements.

Superior Labs VasoWORx

Review: Superior Labs VasoWORx contains 7 blood flow increasing ingredients and no stimulants.

This unique blend has Quercetin, ALAs and grape seed extract, all known vasodilators, plus the usual suspects, L-Citrulline, B3 and AAKG to give you vein producing pumps without tingly or jittery side effects.

This supplement also aids in lowering blood pressure.


  • Contains Quercetin, ALA’s and Grape seed extract vasodilators.
  • No artificial colors, fillers or junk.
  • 90 servings per container, a good value.


  • Contains a proprietary blend, meaning actual doses of some ingredients are not specified.


Good capsule for blood vessel dilation, vascular pumps and lowering blood pressure.

M2 Pre-Workout

Review: They might have named this vasodilation supplement M2 because it does two things well, gives excellent vascular pumps, and packs a strong punch of energy.

One of my favorite aspects of this pre-workout drink is the generous dose of each vasodilating ingredients. My next favorite aspect is the variety of stimulants including caffeine, synaphrine, Teacrine Yohimbine and 2-aminoisoheptane. Careful!


  • 6 grams of pump producing Citrulline malate, 2 grams of vasodilation Taurine and 4 grams of Beta Alanine.
  • Contains a good mix of stimulants to power your workout routine.
  • 20 mg of vasodilating niacin.


  • High Beta Alanine may give tingles. Also, this formula contains strong stimulants.


Powerful energy and impressive pumps make this one of the best vasodilator supplements for oomph and volume.

Dr. Jekyll NitroX

Review: The Dr. Jekyll formula includes ingredients that raise NO and extend the effects of NO once it has been elevated.

What’s more, this formula also contains powerful stimulants like Teacrine, a long lasting cousin of caffeine, and 100 mg of caffeine also.


  • 5 g of L-Citrulline and .5 gram Arginine.
  • Contains Niacin and L-Norvaline.
  • Great value with 30 serving per container.
  • Contains Energy and focus enhancers in addition to Vasodilating ingredients.


  • Uses artificial colors and sweeteners.


Just what the Dr. ordered for long lasting pumps and energy.

PUMPSURGE Stim Free Pre-Workout

Review: I love that Pumpsurge has a fair amount of 5 grams L-Citrulline which is more potent that the Malate version of Citrulline.

In addition to that, the formula contains Astragin, a combo of astragalus root and ginseng, which work to make the other ingredients more bioavailable so less is needed to be effective.

This non-stimulant vasodilation supplement also includes ingredients that promote focus and strength.


  • 5 grams of the potent form of Citrulline, L Citrulline.
  • Astragin allows other ingredients to absorb better.
  • Huperzine A promotes laser focus.


  • Contains artificial sweeteners and flavors.


Excellent pre-workout for muscle enhancing pumps, focus and stamina.

Nature’s Pump Pre-Workout

Review: This all natural vasodilator supplement contains 6 grams of pump producing L-Citrulline, plus it supports optimal health with a superfoods complex, and includes ingredients that assist in recover and muscle repair and building.

Looking for more natural and organic pre-workouts? Check out these reviews!


  • 6 grams of superior NO producing vasodilation causing L-Citrulline.
  • All natural! No artificial flavors, colors sweeteners, and no sugar.
  • Completely Free of harsh Stimulants.


  • Expensive per serving.


One of the best natural vasodilator supplements you can get.

Sheer Strength Sheer Pre-X

Review: Sheer Pre-X Pre-workout has ample vasodilation ingredients, a hefty dose of caffeine for a boost in energy and also contains Bioperine, an ingredient that helps other components in this formula work better.


  • 6 grams of vasodilation supplement L-Citrulline Malate.
  • 5 grams of nitric oxide synthase precursor Beta-alanine.
  • 350 mg of energy producing Caffeine.


  • Contains artificial sweeteners and maltodextrin.


Boost Nitric Oxide and energy levels with this synergistic pre-workout drink.

Nordic Clinical’s Nitric Oxide BloodBooster

Review: This carefully formulated vasodilation supplement is designed to increase blood flow and increase NO.

The formula contains a potent version of L-Citrulline for vasodilation, along with L-glutathione which acts as a potentiator of L-Citrulline, making it, and you, go farther and last longer.


  • Contains potent Kyowa Quality L-Citrulline.
  • Uses Setria® L-Glutathione, which is stable during digestion.
  • Includes blood vessel dilating Trans-resveratrol, a more bioavailable form of resveratrol.


  • A little pricy.


Made with scientifically engineered superior ingredients that are more powerful combined.

ZHZOU N.O. Pro Nitric Oxide Supplement

Review: This simple stimulant free capsule uses 4 vasodilating supplements combined to give you vascular pumps, increased blood flow and allows efficient delivery of oxygen and nutrients to your muscles.

It is offered at an affordable price in easy to take convenient capsule form so you can take it on the go.


  • Contains 4 proven vasodilators, L-Arginine, AAKG, Citrulline Malate and Beet Root.
  • Accessible price.
  • Easy to take capsule form.


  • 4 capsule serving size.


An effective vasodilator supplement for pumps, lowering blood pressure and helping out in “other areas”.


Review: UNLSHD VEINZ & Gainz is a simple formula with 4 vasodilation supplements, three different types of creatine, and 300 mg of caffeine for a good wake up call.

Effective and tasty pre-workout drink. Learn more about how creatine will take you to the next level.


  • Includes Pump producing L-Citrulline and Betaine.
  • Includes a dose of three types of creatine, proven to increase lean muscle mass and strength.
  • 300 mg of Caffeine for intense energy.


  • Ingredients listed as a proprietary blend so you do not know dose of each ingredient.


4 Vasodilation Ingredients for veins, and three types of creatine provide the gains.

NutraChamps Nitric Charge

Review: NutriChamps is a Vegan supplement that contains 4 potent vasodilation ingredients including Pine Bark Extract, L-Arginine, AAKG and Citrulline Malate, is easy and convenient capsules so you can take them anytime and anywhere.


  • 2 grams of L-Arginine and AAKG.
  • Contains 150 mg of vasodilator Pine Bark Extract.
  • All natural, no fillers, artificial colors, and made using vegan capsules.
  • Vegan supplement.


  • 4 capsules per serving.


Best natural vasodilator supplement in Vegan Vegetable capsule form.


I searched everywhere and can say with confidence, these are the best vasodilator supplements available today.

Want more?

Looking for supplements for energy and focus? Here we have a list of 15 of the best pre-workouts for energy and focus, including reviews.

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